Jefferson Health is a non-profit health system and the largest in the Philadelphia region, with more than 65,000 people across hospitals and outpatient locations in Greater Philadelphia, South Jersey, the Lehigh Valley and north-eastern Pennsylvania. It operates on a multi-state scale and is the second-largest employer in Philadelphia. Care delivery runs from primary care to advanced specialised treatment, including advanced surgical and transplant programmes.
The system is organised around an integrated model that combines clinical care with medical education and research through a partnership with Thomas Jefferson University. This links hospital operations, academic programmes and research activity within a single organisation, spanning domains such as transplant medicine, advanced surgical procedures, preventive care and community health. Jefferson Health is nationally ranked and nationally recognised for clinical expertise.
Beyond acute services, Jefferson Health runs community health initiatives and preventive care programmes intended to extend its reach into the populations it serves. The organisation describes its mission as "We Improve Lives", with an emphasis on coordinated, patient-centred care, medical innovation and research breakthroughs, and a non-profit, community-oriented structure.






