The U.S. Chamber of Commerce is a business advocacy organization founded in 1912 and headquartered in Washington, D.C. It represents the interests of the American business community across all sizes, from startups and small enterprises to multinational corporations, industry associations, and local chambers. The organization engages with elected officials and regulators at federal, state, and international levels.
The Chamber's work spans policy advocacy, regulatory engagement, research and publications, and workforce initiatives. Its technical footprint includes the CO digital platform for small businesses, along with signature programmes such as the State of American Business address and the America Works Initiative, which focuses on employment-related objectives. The organization also operates networking events and educational programming to connect members and inform business strategy.