1. Home
  2. Companies
  3. 1upHealth
1U

1upHealth

About

In 2017, 1upHealth entered the healthcare solutions market with a clear mission: to tackle one of the industry's most pressing challenges - healthcare data. The founders recognized that the US healthcare system was broken, costing more per capita than any other country while delivering poor outcomes, with poor quality data alone costing the industry $300 billion annually. They saw 80% of health data remaining untapped, trapped in unstructured formats or isolated in data silos. So they built 1upHealth - a cloud-native, FHIR-enabled platform designed to unlock the true potential of healthcare data through modern interoperability.

Today, 1upHealth stands as healthcare's modern data platform, making it easy for payers, providers, life sciences companies, and digital health innovators to acquire, manage, and use healthcare data at scale. Built natively in the cloud using FHIR as the foundation, the platform connects to over 10,000 clinical endpoints, enabling seamless data exchange and powerful analytics. Trusted by 75+ enterprise organizations including leading national health plans, CMS ACOs, and state Medicaid agencies, 1upHealth transforms fragmented data into actionable insights that improve care quality, lower costs, and reduce risk. The company is led by a diverse team of healthcare experts, interoperability pioneers, and cloud technologists, including Chief Strategy Officer Dr. Donald Rucker, the former National Coordinator for Health IT who literally wrote the book on healthcare interoperability.

Similar companies

HE

HealthEquity

HealthEquity is on a mission to save and improve lives by empowering healthcare consumers. Every year, millions of Americans struggle to navigate the complex healthcare system while trying to save for future medical expenses. HealthEquity exists to change that - providing individuals and families with powerful tools to take control of their healthcare finances through Health Savings Accounts (HSAs) and other consumer-directed benefits. As a leading HSA administrator and non-bank health savings trustee designated by the IRS, HealthEquity combines financial technology with healthcare expertise to deliver integrated benefits solutions. The company empowers working Americans to build health savings, make informed healthcare decisions, and achieve financial wellness. By offering HSAs, FSAs, HRAs, COBRA, and other benefits administration services, HealthEquity helps employers and financial advisors deliver better value to their teams while giving individuals the choice, control, and confidence they need to manage their healthcare dollars effectively.

IH

Included Health

Included Health combines virtual and in-person care with expert navigation, comprehensive support, and AI-powered technology. By bringing together a diverse team of clinicians, data scientists, and care advocates, the company transforms how people experience healthcare. The mission is to raise the standard of healthcare for everyone, delivering world-class care that improves health outcomes, removes unnecessary costs, and supports the mind, body, and wallet of every member served. In 2021, Included Health joined forces with Grand Rounds Health, a leader in expert medical opinions, and Doctor On Demand, a pioneer in virtual care, to create a new kind of healthcare company. Today, Included Health delivers a clinically-led, tech-enabled care model that connects people to access, answers, and advocacy through three core pillars: Access to high-quality physician-led care across all specialties and settings, Answers powered by AI, data, and clinical expertise, and Advocacy providing administrative support for financial and social well-being.

TE

The Elevance Health Companies, Inc.

At Elevance Health, we believe in transforming healthcare through a whole-health approach that addresses physical, behavioral, and social needs. Our nearly 100,000 associates serve more than 118 million people at every stage of their health journey, guided by our bold purpose to improve the health of humanity. We live by our core values - Community, Diversity, Integrity, Agility, and Leadership - which inspire us to put people first, embrace change, build trust, and lead by example every day. Our culture emphasizes collaboration and continuous learning, fostering an inclusive environment where all associates have the opportunity to succeed. We are evolving from a traditional health benefits organization into a lifetime, trusted health partner, powered by industry-leading capabilities and a digital platform for health. Through our family of companies including Anthem Blue Cross, Carelon, and Wellpoint, we deliver integrated solutions that promote whole health and advance health beyond healthcare for the consumers and communities we serve.

HH

Highmark Health

At Highmark Health, we believe in the power of collaboration to transform healthcare from a fragmented system into a unified, compassionate experience. Our team of more than 35,000 people works together across eight companies to create remarkable health experiences that free people to be their best. We operate as a blended health organization, meaning our teams don't work in silos - they collaborate across health insurance, hospital systems, dental care, vision services, and technology solutions to provide seamless, coordinated care for our members and patients. We're deeply rooted in our communities, with a legacy of compassionate care that spans more than 175 years. This tradition of giving back isn't just a policy - it's woven into our daily culture. Our team members thrive in an environment that values purpose-driven work, continuous innovation, and meaningful community impact. We challenge the status quo at every touchpoint, embracing breakthrough ideas and new visionaries who champion change in the American healthcare system. Together, we're building something stronger than the sum of our parts - a healthcare experience that genuinely cares for people.

JH

Judi Health

In 2017, AJ Loiacono and Ryan Kelly founded Capital Rx with a singular mission: to transform the broken prescription drug pricing system that was costing patients and plans billions. They recognized early on that the traditional pharmacy benefit manager (PBM) model was riddled with hidden fees, opaque pricing, and misaligned incentives that prioritized profits over patient care. Rather than simply building another layer of technology on top of existing systems, they made the bold decision to become a full-service PBM themselves, developing their own platform from the ground up that would enable unprecedented transparency and efficiency. What began as a focused effort to revolutionize pharmacy benefits quickly evolved into something much larger. As they built their technology platform, they realized that to truly transform healthcare, they needed to address the entire health benefits ecosystem - not just pharmacy. They developed Judi®, an open, secure, and scalable enterprise health platform that could unify claims processing across pharmacy, medical, dental, and vision benefits. This breakthrough platform enabled the launch of Judi Health™, the industry's first Unified Claims Processing™ platform, which eliminates administrative waste and redundancies by bringing all benefits together in one system. In 2025, Capital Rx rebranded to Judi Health to reflect this expansion beyond pharmacy, marking the company's evolution into a full-stack health infrastructure platform that's building the digital foundation needed to make healthcare accessible, affordable, and transparent for all.

GH

Global Healthcare Exchange (GHX)

Every year, billions of dollars in healthcare supply chain transactions still move through manual, fragmented processes that waste time, increase costs, and drain resources that could be devoted to patient care. GHX exists to transform this reality - building the largest cloud-based supply chain network in healthcare that connects providers, suppliers, and distributors in a synchronized digital ecosystem. Founded in 2000 by industry leaders including GE, Johnson & Johnson, Abbott, Baxter, and Medtronic, GHX has spent over two decades proving that when healthcare organizations collaborate through shared technology and data, the entire industry benefits. The company's mission is to simplify the patient-centered business of healthcare to improve outcomes, and they're delivering measurable results: more than $2 billion in industry savings annually, 18,000+ healthcare facilities connected, and 166 million+ purchase orders and invoices processed through the GHX platform each year. GHX solutions span the entire supply chain - from value analysis and clinical evidence to automated ordering, inventory management, electronic invoicing, and vendor credentialing - all designed to eliminate costs rather than just shift them. By replacing supply chain fragility with resilience through intelligent automation and data-driven insights, GHX enables hospitals to focus on delivering quality care while suppliers can continue creating life-saving products.